Optical genome mapping of large structural variations in non-inflammatory and inflammatory breast cancer

Vanderbilt University Medical Center
January 26, 2021
 

Dr. Justin Balko

Dr. Justin Balko, Vanderbilt University Medical Center presents his work on inflammatory breast cancer, a form of breast cancer that has a poor prognosis and responds poorly to treatment. Using Saphyr, he was able to identify recurring structural variants in a gene that was never before associated with breast cancer and may be a critical factor that defines this aggressive disease. He concludes that in cases like inflammatory breast cancer where sequencing and other techniques have been exhausted, OGM offers a unique opportunity to find critical variants.