Human Papilloma Virus Integration Strictly Correlates with Global Genome Instability in Head and Neck Cancer

Dr. Jim Broach, Director of the Penn State Institute for Personalized Medicine presents on HPV-induced head and neck cancer, one of the few cancers on the rise in the US while most other cancers continue to decline. OGM allowed his team to reconstruct complicated genomic changes that next-generation sequencing hasn’t been able to identify. He concludes that Saphyr is a powerful tool to identify and characterize viral integration in tumors and that it can detect the genome instability associated with HPV integration.