Analysis of Genomic Complexity in Patients with Chronic Lymphocytic Leukemia by Bionano Genomics Optical Mapping

Dr. Blanca Espinet and Dr. Anna Puiggros, Hospital del Mar in Barcelona, Spain presented their study on Chronic Lymphocytic Leukemia (CLL), comparing Saphyr results on 10 non-complex and 12 complex CLL samples against Cytoscan HD and karyotype. Early conclusions for the study show that Saphyr detected most of the previously known abnormalities but provided additional structural information and detected many additional genomic abnormalities, making it a valuable tool to assess genomic complexity.