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Cancer Genomics: Heme Malignancies and
Solid Tumor Research

To get a complete picture of highly rearranged cancer genomes in heterogeneous samples, you need long range information at high coverage and analysis tools with high sensitivities and low false positives. Bionano optical genome mapping collects up to 1600x coverage of a human genome to uncover large structural variations beyond what short and long read sequencing can see, at variant allele fractions as low as 1%.

Unbiased, genome-wide SV detection at
1% allele fraction

Cancer samples are just too complex for low coverage whole genome sequencing. Complex rearrangements, tumor heterogeneity and unsequenceable repetitive regions of the genome present additional challenges for short and long read sequencing technologies.

Bionano Saphyr Genome Imaging Instrument finds structural variations larger than 500 bp, unbiased and genome-wide, with the highest sensitivities and the lowest false positive rates, down to 1% variant allele fraction.

Our tools and platforms provide unparalleled structural variation detection for cancer research.


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