In The Media

Genetic Engineering & Biotechnology News
November 27, 2019
CU Anschutz Medical Campus
September 18, 2019
Genetic Engineering & Biotechnology News
September 4, 2019
April, 2017
The Scientist
December, 2014
2013 Medical Design Excellence Awards
June, 2013
Nature Methods
August, 2012
Nature Biotechnology
August, 2012
Genetic Engineering & Biotechnology News
July, 2012
Research at Princeton
December, 2011
Medical Device and Diagnostic Industry
June, 2010
Karow, Julie – Genomeweb, "In Sequence."
October, 2009
Lawinski, Jennifer –
March, 2009
Gravitz, Lauren – MIT Technology Review
February, 2009

Press Releases


November 16 - November 20
Nashville, TN, USA
Booth: 18
June 20 - June 23
Sevilla, Spain
November 1 - November 5
Phoenix, AZ, USA
October 25 - October 29
Los Angeles, CA, USA
July 31 - August 3
St. Louis, MO, USA
Booth: 148
June 11 - June 14
Vienna, Austria
May 15 - May 18
Hilton Head, SC, USA


Learn more about Bionano at ACC.

Booth: 4021
April 8 - April 13
New Orleans, LA, USA


Find out more about Bionano at AACR!

January 10 - January 13
Virtual event

Symposium was hosted January 10 – 13, 2022, with over 4,000 registrants from 82 countries. This four-day virtual event featured 31 oral presentations and 37 scientific posters from genomic scientists at leading institutions, who reported their use of OGM and its utility for genetic disease and cancer applications. Each day focused on four key clinical areas: constitutional cytogenomics, hematologic malignancies, solid tumors, and OGM + NGS.

If you missed the live event, it’s not too late! On-demand presentations are available with free registration at


 - June 29
Virtual - Online

Facioscapulohumeral muscular dystrophy (FSHD) is associated with the contraction of the D4Z4 macrosatellite in the 4q35 subtelomeric region. The most common technique for genetic diagnosis of FSHD is Southern Blotting which is tedious, difficult to interpret, and involves radioactive labelling, which limits its availability. In this webinar, molecular geneticist Jeroen Depreeuw, PhD, from Centrum Menselijke Erfelijkheid, UZ Leuven, discusses the potential of a new technique, called Optical Genome Mapping (OGM) with the Saphyr system from Bionano Genomics for FSHD detection. Based on the Leuven team’s validation study, they conclude that OGM is a powerful and robust technique for FSHD testing in genetic diagnostic laboratories, providing results that are completely concordant with the current gold standard Southern Blot analysis. Dr. Depreeuw will present details of the validation study and take questions from the audience.

 - June 30
Virtual - Online

Join us to discover how Optical Genome Mapping (OGM) can help you in the characterization of complex samples. OGM is a non-sequencing technique that provides a high-resolution view of intact, long DNA molecules free from the bias and errors introduced by Next-Generation Sequencing. Automatically identify all structural variants, genome-wide, starting at 500bp, including complex rearrangements and with sensitivity down to 1% allele fraction. Structural variants have nowhere to hide.

 - April 28
Virtual - Online - 7:00A PDT / 10:00A EDT

Host genome analysis of structural variations by Optical Genome Mapping in patients with severe COVID-19

Ravindra Kolhe, MD, PhD
Department of Pathology, Section of Anatomic Pathology
Vice Chairman for Translation Research
Chief, Section of Molecular and Genetic Pathology
Augusta University

The varied clinical manifestations and outcomes in patients with SARS-CoV-2 infections implicate a role of host-genetics in the predisposition to disease severity. This role is supported by evidence that is now emerging, where initial reports identify common risk factors and rare genetic variants associated with high risk for severe/life-threatening COVID-19. We investigated the host genomes of individuals with severe/life-threatening COVID-19 at the structural variant level (500 bp – Mbps) to identify events that might provide insight into the inter-individual variability in clinical course and outcomes associated with SARS-CoV-2 infections and COVID-19 mortality.

 - March 24
Virtual - Online - 7:00A PST / 10:00A EST

Advanced structural analysis of risk loci for congenital diaphragmatic hernia using optical genome mapping technology
Frances High, MD, PhD
Assistant in Pediatrics, MassGeneral Hospital for Children
Assistant Professor of Pediatrics, Harvard Medical School

In this webinar, Dr. Frances High will explore how she used Bionano’s Saphyr system for optical genome mapping to analyze structural variations in a large cohort of patients with CDH and their parents, and how it has led to the identification of critical genes and pathways creating improved understanding of the disorder.

January 1 - December 31
Click Bionano Logo or Text Above for More Information
November 16 - November 20
Virtual - Online


Register now to join us for our corporate workshop on

Thursday, November 18th from 9:00 am – 9:50 am EST.

Combining Optical Genome Mapping (OGM) with Next-Generation Sequencing (NGS) Data to Provide the Most Comprehensive Genome Analysis for Oncology Applications
We’ll explore how the combination of OGM with NGS data enables the most comprehensive picture of the genome. In this session you’ll learn about the functionality of BioDiscovery’s Nx Clinical software for data interpretation of hematological malignancy and solid tumor samples in a clinical research setting.

October 19 - October 23
Hybrid - Virtual / In-Person
August 1 - August 4

Bionano Showcase:
Monday, August 2, 2021 | 12:35 – 1:20 PM EDT
Ushering in a New Era for Cytogenomics Based on Optical Genome Mapping
Alka Chaubey, Bionano Genomics

Followed by a panel discussion featuring:

Ravindra Kolhe, Augusta University
Adrian Lee, University of Pittsburgh Medical Center
Alan Lennon, Pathgroup

Sunday, August 1, 2021:
1:25 – 2:25 PM EDT Session 1: Brain Tumors – Molecular Landscape and Emerging Targets
Optical Genome Mapping Reveals Novel Structural Variants in Pediatric High Grade Gliomas
Miriam Bornhorst, Children’s National Hospital

Monday, August 2, 2021:
10:10 – 11:10 AM EDT Session 2: New Strides in Technology
Adoption of Optical Genome Mapping in Clinical Cancer Cytogenetics Laboratory: A Stepwise Approach
Victoria Stinnett, The Johns Hopkins University

3:25 – 4:10 PM EDT Session 3: New Molecular Insights into Myeloid Hematologic Malignancies
Optical Genome Mapping for Chromosomal Structural Variants Analysis in Hematological Malignancies
Rashmi Kanagal-Shamanna, MD Anderson Cancer Center

5:40 – 6:25 PM EDT Session 4: Integrating Genomics into Constitutional Analysis
Next-Generation Cytogenetics: Proposal for a Cost-Effective Approach for Comprehensive Testing of Prenatal Cases
Nikhil Sahajpal, Augusta University

Tuesday, August 3, 2021:
3:20 – 4:05 PM EDT Session 6: Genetic Spectrum of Vascular Anomalies and Overgrowth Syndromes
Genomic Structural Variations in Lymphatic Anomalies
Thuy Phung, University of South Alabama

5:30 – 6:15 PM EDT Session 7: Hematologic Malignancies
Complementarity of RNA Sequencing and Optical Genome Mapping in Detection of Rare Fusions in Pediatric B-ALL
Gordana Raca, Children’s Hospital Los Angeles

Wednesday, August 4, 2021:
5:30 – 6:30 PM EDT Session 11: Unraveling Solid Tumors with Genomic Technologies
Clinical Utility and Feasibility of Adopting Optical Genome Mapping for Chromosomal Characterization of Solid Tumors
Nikhil Sahajpal, Augusta University
*Second Place Technologist Abstract Award

Integrative Cytogenomics Studies Using Optical Genome Mapping in Two Cases with Chronic Lymphocytic Leukemia
Jia-Chi Wang, City of Hope National Medical Center

On-Demand Poster Presentations:
Optical Genome Mapping and SNP Microarray: Integrated Workflow for Optimizing Analysis of Products of Conception
Nikhil Sahajpal, Augusta University

Optical Genome Mapping Reveals Genomic Complexity and Detects Novel Genetic Abnormalities in T-Lymphoblastic Leukemia
Guilin Tang, MD Anderson Cancer Center

August 28 - August 31
Virtual - Online

Live Sessions Featuring Bionano Data at ESHG 2021
(All times listed in CEST)

Sunday, August 29 – 13:15-13:30
C09.6 – Long-read technologies identify a hidden inverted duplication in a family with choroideremia
Kornelia Neveling, Radboud University Medical Centre, Netherlands

C13.6 – Germline chromothripsis of the APC locus in a patient with adenomatous polyposis
Florentine Scharf, Medical Genetics Center Munich, Germany

Monday, August 30 – 15:30-16:30
CS036 Bionano Corporate Satellite
Bionano Genomics: Enlightening the dark matter of the genome
Yannick Delpu, PhD, Bionano Genomics
2. Optical Genome Mapping identifies germline retrotransposon insertion in SMARCB1 in two siblings with Atypical Teratoid Rhabdoid Tumor
Mariangela Sabatella, PhD, Princess Maxima Center for Pediatric Oncology

Tuesday, August 31
C24.1 – What is the best solution to manage failures of chromosomal structural variations detection by short-read strategy?
Caroline Schluth-Bolard, Universite Hospital de Lyon, France


E-Poster Area
Available for Attendee Viewing beginning Saturday, August 28 – 9:00A-6:00P CEST

Track: Neuromuscular Disorders

P10.025.A / A – Bionano optical genome mapping and southern blot analysis for FSHD detection

Jeroen Depreeuw, Barbara Dewaele, Sascha Vermeer, Gert Matthijs, Valérie Race;
Ctr. for Human Genetics, Univ. Hosp. of Leuven, Leuven, Belgium.

Track: Cancer Genetics

P12.188.D / D – Efficient workflow for detection of clinically relevant abnormalities in leukemias according to NCCN guidelines.

Alex Hastie, Andy W. C. Pang, Joyce Lee, Ernest Lam, Mark Oldakowski, Alka Chaubey;
Bionano Genomics, San Diego, CA.

Track: Genome Variation and Architecture

P13.006.C / C – High throughput analysis of disease repeat expansions and contractions by optical mapping

Dong Zhang, Ernest Lam, Jian Wang, Tom Wang, Andy Pang, Henry Sadowski, Alex Hastie, Mark Oldakowski;
Bionano Genomics, San Diego, CA

Track: Cytogenetics

P14.002.C / C – 16p13.11p11.2 triplication syndrome: a new recognizable genomic disorder characterized by Bionano optical mapping and whole genome sequencing

Romain Nicolle1,2, Karine Siquier-Pernet2, Marlène Rio2,3, Anne Guimier3, Emmanuelle Olivier4, Patrick Nitschke4, Christine Bole-Feysot5, Serge Romana1,2, Alex Hastie6, Vincent Cantagrel2, Valérie Malan1,2

P14.023.D / D – Characterization of breakpoint regions of apparently balanced translocations by optical genome mapping
Jenny Schiller1, Karolina Bilska1, Uwe Heinrich1, Eva-Maria Krimmel1, Stephanie Demuth2, Imma Rost1;

P14.024.A / A – Optical genome mapping: a cytogenetic revolution
Valeria Orlando1, Silvia Genovese1, Laura Ciocca1, Viola Alesi1, Sara Loddo1, Silvia Di Tommaso1, Marina Trivisano2, Maria Lisa Dentici3, Alessandro Ferretti2, Antonio Novelli1;
11- Lab. of Med. Genetics, Translational Cytogenomics Res. Unit, Bambino Gesù Children Hosp., Roma, Italy, 22- Rare and Complex Epilepsy Unit, Dept. of Neuroscience, Bambino Gesù Children Hosp., Roma, Italy, 33- Med. Genetics Unit, Academic Dept. of Pediatrics, Bambino Gesù Children Hosp., Roma, Italy.

Track: New Technologies and Approaches

P15.002.B / B – The clinical utility of optical genome mapping for the assessment of genomic aberrations in acute lymphoblastic leukemia
Jonathan L. Lühmann1, Marie Stelter1, Marie Wolter1, Josephine Kater1, Jana Lentes1, Anke K. Bergmann1, Max Schieck1, Gudrun Göhring1, Anja Möricke2, Gunnar Cario2, Martin Schrappe2, Brigitte Schlegelberger1, Martin Stanulla3, Doris Steinemann1;
1Dept. of Human Genetics, Hannover Med. Sch., Hannover, Germany, 2Dept. of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts Univ. Kiel and Univ. Med. Ctr. Schleswig-Holstein, Kiel, Germany, 3Pediatric Hematology and Oncology, Hannover Med. Sch., Hannover, Germany.

P15.035.C / C – Optical Genome Mapping: where molecular techniques give up
Alesi1, F. Lepri1, S. Genovese1, V. Orlando1, S. Loddo1, S. Di Tommaso1, M. Luciani2, F. Deodato3, R. Capolino4, A. Novelli1;
1Laboratory of Medical Genetics, Translational Cytogenomics Research Unit, Bambino Gesù Children’s Hospital, Rome, Italy, 2Haemophilia Centre, Bambino Gesù Paediatric Hospital, Rome, Italy, 3Division of Metabolism, Bambino Gesù Children’s Hospital, Rome, Italy, 4Genetics and Rare Diseases Research Division, Bambino Gesù Children’s Hospital, Rome, Italy.

Track: Diagnostic Improvements and Quality Control

P16.036.C / C – Identification of structural variation in constitutional disorders by optical genome mapping

Andy Wing Chun Pang, Alex Hastie, Alka Chaubey;
Bionano Genomics, San Diego, CA.

June 9 - June 12
Abstract Submission Deadline: March 8
June 4 - June 8
Abstract Submission Deadline: February 17
May 9 - May 12
Virtual - Online
April 13 - April 16
Virtual - Online
April 10 - April 15
Virtual - Online
October 27 - October 31
San Diego, CA
November 17 - November 21
Vancouver, British Columbia
June 6 - June 9
Sponsor / Corporate Satellite Session - Sunday, June 7 @ 12:00P CEST (UTC+2)

Session: CS15 – Bionano Genomics Satellite: High throughput Genome Imaging for the detection of Structural Variation in Genetic Disease & Cancer 
Type: 08. Corporate Satellites 
Date & Time: Sunday, June 7, 2020 – 12:00 – 13:00 CEST
Room: Virtual Session Room 2

August 3 - August 4
Platinum Sponsor
June 25 - June 26
June 22 - June 24
June 12 - June 12
Brandon LaBarge - MD - Penn State Health / Otolaryngology - Head and Neck Surgery Resident
Learning Objectives:
1) Understand the solid tumor high-molecular weight DNA isolation process
2) Review whole genome imaging findings of head and neck cancers
 - October 14
Marriott Marquis Houston, 1777 Walker Street, Houston, TX, 77010


Click here to view the agenda.