• Application

  • Implementation

Upcoming Webinars

Resolving Complex Haplotypes Implicated in Alzheimer’s and Other Neurodegenerative Diseases
Mayo Clinic
Dr. Mark T. W. Ebbert

Alzheimer’s disease is genetically complex with no meaningful therapies or pre-symptomatic disease diagnostics. Most of the genes implicated in Alzheimer’s disease do not have a known functional mutation, meaning there are no known molecular mechanisms to help understand disease etiology.

In this webinar, Mark T. W. Ebbert of the Mayo Clinic wil...

August 26, 2020 at 8:00A PDT | 11:00A EDT | 5:00P CET
If you are unable to attend the webinar, register to receive the recorded version for viewing at a later time.

Webinar Archive

Radboud Medical Center, Nijmegen, The Netherlands
Alexander Hoischen, PhD

Cytogenetics with 500,000 “bands”

~ 10,000 Improved Sensitivity!

  • Genomewide analysis
  • Positional information
  • Single molecule resolution
Children's National Medical Center
Dr. Hayk Barseghyan

You have a lot of great genomics data – so, what’s next?

In this webinar, we will explore tools and methods to analyze structural variation and demonstrate how to cut through the noise.

Genome imaging with Bionano’s Saphyr generates high quality structural variation calls for less than $500 per sample, with up to 99% sensitivi...

University of California, San Diego
Dr. Vineet Bafna

Oncogene amplification, a major driver of cancer pathogenicity, is often mediated through focal amplification of genomic segments. Recent results implicate extrachromosomal DNA (ecDNA) as the primary driver of focal copy number amplification (fCNA) – enabling gene amplification, rapid tumor evolution, and the rewiring of regulatory circuitry. Res...

Virtual Genetics Week 2020
Dr. Sven Bocklandt

The diagnostic yield in genetic disease has seen very little improvement over the last few decades, despite the introduction of whole genome sequencing.

The Bionano Genomics platform for genome imaging offers an extremely long-read technology, providing unmatched sensitivity and specificity to detect structural variation, genome-wide, at low cos...

Paris Descartes University / Radboud Medical Center
Laila El Khattabi, PharmD PhD | Alexander Hoischen, PhD

Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well as cancer. SVs are enriched in repeat-rich regions of the human genome, and several remain undetected by conventional short-read sequencing technologies. Here we applied Bionano Genomics’ high-resolut...

Penn State Health
Dr. Brandon LaBarge

Whole genome imaging using the Saphyr instrument from Bionano detects structural variants (SVs), such as insertions, deletions, and translocations, not readily evident from standard methods of whole genome analysis. This technology is particularly useful for detecting large (>500bp) and complex SVs that are difficult to detect using traditional shor...

Accurate analysis of structural variants begins with isolating ultra-high molecular weight DNA. Obtaining high-quality UHMW DNA can present a challenge since sample collection, preservation, the DNA isolation process and subsequent handling of isolated DNA can significantly affect its quality.

In this webinar, Dr. Ben Clifford, Sr. Application S...

Cordelier Research Center - Paris
Dr. Eric Letouzé

“Bionano’s optical mapping technology allowed us to characterize complex structural rearrangements in cancer with unprecedented precision. The results are incredibly robust and easy to interpret with Bionano software, and the team was really helpful for data analysis!”
-Dr. Eric Letouzé

Cyclins A2 and E1 regulate the cell...