Identify rare and new fusions of known genes

In a large systematic comparative study between optical mapping and classical cytogenetics, Bionano identified novel, non-recurrent fusions never reported before. In both cases shown here, one of the two fusion partners is well known in leukemia from other gene fusions. These events were missed by classical cytogenetics either because of their low allelic frequencies or because of the targeted FISH approach classically used in a diagnostics context.