OGM demonstrates high concordance with traditional cytogenetic methods

OGM demonstrated 100% concordance with karyotyping, FISH, and chromosomal microarray in constitutional disorders in two studies appearing in the July 2021 issue of the American Journal of Human Genetics (AJHG).

The authors in these back-to-back publications describe OGM as a better alternative to traditional cytogenetic assays for both inherited genetic disease and hematologic malignancy applications since it consolidates multiple antiquated methods requiring manual integration for interpretation into a single workflow with higher resolution for detection of all classes of structural variants.