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  • Bionano Access Software is the Perfect Companion to Saphyr

The Bionano Saphyr™ system is our highest speed, highest throughput genome mapping system to date. In order to help our customers get the most from this system, we developed a new software suite called Bionano Access™.

Bionano Access makes managing the Bionano workflow easy and convenient for everyone, regardless of where they are and the devices they have available.

Bionano Access is not only more powerful and versatile than our previous experiment management software, IrysView, it is engineered to perfectly complement our Saphyr genome mapping platform. Now, setting up experiments, controlling instrument runs, managing data analysis and visualizing genome maps is faster and easier than ever.

Bionano Access functions as a web server that can be installed anywhere on your network and accessed via any web browser. We also designed the user interface (UI) to be lightweight and resource-friendly for mobile devices so you can monitor runs on a smartphone or tablet.

When connected to Saphyr, you can use Access to set up experiments and start and monitor runs. Access also provides a dashboard (Figure 1) where you can monitor the progress of the run and view real-time data metrics such as the amount of data collected and the alignment rate.

Figure 1. Bionano Access dashboard view for monitoring run progress.

Bionano Irys® users reap benefits from Access as well. Access can control the Bionano Solve pipeline to start assemblies, hybrid scaffolding tasks and structural variation analyses.

Bionano Access also features new visualization tools that allow you to visualize genome maps and structural variation calls (Figure 2). With Access visualization tools you can perform a variety of tasks, including:

  • Direct inspection and editing of genome maps
  • Viewing conflicts between the NGS assembly and Bionano maps in hybrid scaffold applications
  • Loading structural variation calls and the corresponding map-to-reference alignment and visually inspecting the calls

Figure 2. Bionano Access structural variation (SV) visualization view of the analysis of SV calls and the underlying alignment. The sample shows a repeat expansion relative to the reference Hg19 (in green) identified in two independent Bionano assemblies, labeled with Nt.BspQI (above reference) and with Nb.BssSI (below ref). Single molecule support for the consensus maps (in blue) is also shown. The SV table (bottom of figure) enables easy navigation of the SV calls.

Ready to try Bionano Access? It’s available as a free download for Windows® and Linux/Mac systems on our Software Downloads page.

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