• Application

  • Implementation

Publications

Trend in Plant Science (2016) 
Chaney et al
Plant Cytogenetics 2015 
Cheng et al
Nucleic Acids Research (2015); 10:1093 
Grunwald, Assef, et al.
Functional & Integrative Genomics (2015); 15 (2): 121-129 
Appels, R., et al.
Genome Research (2014); 24: 2066-2076 
Steinberg, K. et al.
BioMed Central Genomics (2014); 15(July 2014): 387 
O’Bleness, M., et al.
Nano Letters (2012); 12(7): 3861-6 
Baday, M., et al.
Chemical Society Reviews (2010); 39, 985 – 999 
Persson, F., et al.
Nucleic Acids Research (2007); 35(3):e16 
Xiao, M et. al.
Physical Review Letters. (2005); 94, No. 19: 4 
Reisner, W., et al.
PNAS (2005); 102, No. 29: 10012-10016 
Riehn, R., et al.
PNAS (2005); 102, No. 28: 9796-9801 
Wang, Y. M., et al.
PNAS (2004); 101:10979-83 
Tegenfeldt, J.O., et al.
Anal Bioanal Chem (2004); 378: 1678-92 
Tegenfeldt, J. O., et al.
IEEE Transactions on Nanotechnology (2002); 1:12 
Austin, R.H., et al.
Applied Physics Letters (2002); 81:174 
Cao, H., et al.
PNAS (2010); 107(30) 13294-13299 
Reisner, W., et al.

Videos

University of California San Francisco, USA
Dr. Kwok discusses Bionano structural variant discovery in human diseases
Institute of Experimental Biology, Czech Republic
Dr. Dolezel discusses Bionano genome mapping and plant genetics
Brigham Young University,
USA
Dr. Udall discusses Bionano mapping and the cotton genome
Kansas State University,
USA
Dr. Brown shares how Bionano genome maps help validate assemblies
Garvan Institute for Medical Research, Australia
Dr. Hayes discusses how Bionano aids her work prostate cancer

Webinars

Vanessa Hayes
Garvan Institute of Medical Research
Dr. Vanessa Hayes, PhD
Eric Vilain
Chief of Medical Genetics at UCLA
Dr. Eric Vilain, MD, PhD
Alex Harkess
Donald Danforth Plant Science Center
Alex Harkess
Florian Jupe
Salk Institute of Biological Studies
Florian Jupe
Wellcome Trust Sanger Institute
William Chow
Kansas State University
Dr. Sue Brown
Wageningen University
Dr. Gabino Sanchez Perez
Icahn School of Medicine at Mount Sinai
Dr. Ali Bashir and Dr. Bobby Sebra
The Genome Institute at Washington University
Tina Graves
Institute of Experimental Botany, Olomouc
Dr. Jaroslav Dolezel
Emory University
Dr. Michael Rossi

Posters

March, 2017
ACMG Annual Clinical Genetics Meeting, Phoenix, Arizona
February, 2017
Advances in Genome Biology and Technology 2017 General Meeting, Hollywood, FL
February, 2017
Advances in Genome Biology and Technology 2017 General Meeting, Hollywood, FL
February, 2017
Advances in Genome Biology and Technology 2017 General Meeting, Hollywood, FL
January, 2017
Plant and Animal Genome Conference XXV, San Diego, CA
February, 2015
Advances in Genome Biology and Technology, Marco Island, FL

Literature

white papers

This White Paper explains how NGS fails to adequatly analyze repetitive parts of the genome and large structural variation. Bionano’s Next-Generation Mapping is able to detect all SV types with high sensitivity and specificity, and examples of biologically important large structural variants in plant and animal genomes are shown.

white papers

This White Paper explains how NGS leaves half of patients with genetic disorders without a molecular diagnosis, because it fails to adequatly analyze repetitive parts of the genome and large structural variation. Bionano’s Next-Generation Mapping is able to detect all SV types with high sensitivity and specificity, and examples of cancer and genetic disease are shown.

white papers

This white paper explains how Bionano NGM can make any sequency assembly up to 100 times more contiguous by scaffolding sequence contigs, and more exact by correcting errors. The new two-enzyme hybrid scaffold pipeline introduced here improves both aspects. It creates functional genomes at a low cost, no matter what your sequencing strategy is.

white papers

Scientists at Rutgers University, Washington University, and Ibis Biosciences successfully deployed Next-Generation Mapping (NGM) technology from Bionano Genomics to help produce the first complete assembly for a fast-growing aquatic plant with biofuel potential. What emerged is a clear view into a genome undergoing drastic reduction and a tool to elucidate chromosome-scale dynamics.

case studies

This Case Study demonstrates the power of combining 2 single molecule technologies to produce Gold-quality genomes. Those allow the discovery of substantial amount of structural variation unique to individuals and populations otherwise not accessed by other short-read technologies.

case studies

This Case Study highlights Scientists at the USDA and Cold Spring Harbor Laboratory who know that better breeding of maize to feed a growing population will depend on an accurate reference assembly. They tackled the previously intractable crop with a combination of PacBio® Sequencing and BioNano Genomics®genome maps, leading to the first-ever high-quality reference assembly.